About the Product

What it is: A dermatologist-tested, anti-aging night cream with Purified Peptides, Vitamins B3 and B5, and botanical extracts that visibly reduces the look of fine lines and wrinkles in 2 weeks, hydrates for up to 48 hours, and leaves skin looking rested, glowing, and revitalized — a retinol alternative that is hypoallergenic, fragrance-free, and gentle enough for nightly use on sensitive skin.

Item Form: Cream | Skin Type: Sensitive | Size: 1.7 fl. oz. | Use: Face | Application Time: Nighttime | Special Feature: Anti-Aging

What Else You Need to Know: The Cetaphil Healthy Renew Night Cream is a rich, effective yet gentle anti-aging night treatment specifically formulated for sensitive skin that cannot tolerate retinol. Its Purified Peptides deliver the same visible anti-aging benefits as retinol — reducing the look of fine lines and wrinkles — without the typical adaptation time, irritation, or increased sun sensitivity that retinol can cause. Vitamins B3 and B5 hydrate, soothe, and restore the skin's natural moisture barrier, while botanical extracts target visible dullness and uneven skin tone for a more radiant, revitalized complexion by morning. Hypoallergenic, fragrance-free, paraben-free, and dermatologist-tested for nightly use on sensitive skin.

Why It Works — Key Ingredients:

• Purified Peptides (Retinol Alternative): A gentle yet effective alternative to retinol that visibly reduces the look of fine lines and wrinkles in as little as 2 weeks, without requiring adaptation time or increasing sensitivity to the sun — making it ideal for sensitive skin that cannot tolerate traditional retinol formulas.
• Niacinamide (Vitamin B3): Hydrates, soothes, and restores the skin's natural moisture barrier while targeting visible dullness and uneven skin tone for a brighter, more even complexion with consistent nightly use.
• Provitamin B5 (Panthenol): Soothes and conditions the skin overnight, supporting the skin's natural moisture barrier and leaving it feeling soft, supple, and comfortable by morning.
• Botanical Extracts: A blend of skin-brightening botanical actives that target visible dullness and uneven skin tone, working overnight to reveal a more radiant, revitalized, and glowing complexion.

Ingredient Callouts: Purified Peptides. Niacinamide (Vitamin B3). Provitamin B5. Botanical Extracts. 48-hour hydration. Visibly reduces fine lines and wrinkles in 2 weeks. Retinol alternative. Hypoallergenic. Fragrance-free. Paraben-free. Dermatologist-tested. Suitable for sensitive skin.

What It Does:

• Visibly reduces the look of fine lines and wrinkles in as little as 2 weeks
• Hydrates for up to 48 hours and leaves skin looking rested, glowing, and revitalized
• Provides effective anti-aging benefits with Purified Peptides as a gentle retinol alternative
• Hydrates, soothes, and restores the skin barrier with Vitamins B3 and B5
• Targets visible dullness and uneven skin tone with botanical extracts
• Defends against 5 signs of skin sensitivity — dryness, irritation, roughness, tightness, and a weakened barrier

How to Use:

• Apply to clean, dry skin on the face every evening before bed.
• Massage in gentle upward circular motions until fully absorbed.
• Use as the final step in your nighttime skin care routine, after serums and treatments.
• Follow with a morning moisturizer with SPF as part of your daytime routine.
• Use consistently every night for best anti-aging and hydration results, with visible improvement in fine lines and wrinkles expected within 2 weeks.

Ingredients: Please consult the packaging of the product purchased for the full and exact ingredient list, as formulations may be subject to change.

This list of ingredients may be subject to change. Please consult the packaging of the product purchased for the exact ingredient list.